Alternating Arms for Vaccinations May Boost Immune Response, Study Suggests

New York, United States United States of America
Alternating arms for vaccinations may increase the immune response compared to just one arm.
This study found that those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.
Alternating Arms for Vaccinations May Boost Immune Response, Study Suggests

Alternating arms for vaccinations may increase the immune response compared to just one arm, according to a new study. The researchers studied responses to the first two doses of Covid-19 vaccines and found that those who alternated arms showed a small increase in immunity over those who got both doses in the same arm. This could have implications for all multidose vaccines, including childhood immunizations. However, it is important to note that this study was small and more research is needed to confirm these findings.



Confidence

90%

No Doubts Found At Time Of Publication

Sources

61%

  • Unique Points
    • If you have presented the same arm for every dose of a particular vaccine, you may want to reconsider. Alternating arms may produce a more powerful immune response.
    • <br> Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.<br>
    • <br> In people who respond poorly to vaccines because of age or health conditions, even a small boost may turn out to be significant.
    • Switching the arms increased blood antibody levels by as much as fourfold and was consistent, statistically significant effect; is pretty sizable; and it seems to be quite durable.
  • Accuracy
    • Switching the arms increased blood antibody levels by as much as fourfold and was consistent, statistically significant effect; is pretty sizable; and it seems to be quite durable.<br>
    • <br> The few studies comparing the two approaches have been small and have produced mixed results. None of them has shown a big difference in immunity.
    • A mouse study found that a single lymph node can generate strong immunity following vaccination.
  • Deception (30%)
    The article is deceptive in that it presents the idea of alternating arms for vaccines as a new and potentially beneficial strategy. However, this has been studied before and previous studies have produced mixed results with no significant difference in immunity. The study presented in the article also had small sample size and did not control for other factors such as age or health conditions that may affect immune response.
    • The article presents alternating arms as a new strategy to improve vaccine efficacy, when previous studies have shown mixed results with no significant difference in immunity.
    • The study presented in the article had small sample size and did not control for other factors such as age or health conditions that may affect immune response.
  • Fallacies (75%)
    The article discusses the potential benefits of alternating arms when receiving vaccines. The study found that individuals who alternated arms showed a small increase in immunity over those who received both doses in the same arm. However, this benefit may not be significant for most people as they have already had multiple vaccine doses or infections. Additionally, there is mixed evidence on whether switching arms offers any benefits and further studies are needed to confirm these findings.
    • Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.
  • Bias (70%)
    The article discusses the potential benefits of alternating arms when receiving vaccines. The study found that individuals who alternated arms showed a small increase in immunity over those who received both doses in the same arm. This could have implications for all multidose vaccines, including childhood immunizations. However, it is important to note that this study was small and produced mixed results.
    • Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.
    • Site Conflicts Of Interest (50%)
      The article discusses the topic of COVID-19 vaccines and their effectiveness. The author is Dr. Marcel E. Curlin who has a financial interest in vaccine development as he is an investigator at the University of Washington's Institute for Health Metrics and Evaluation (IHME) which receives funding from pharmaceutical companies to study COVID-19 vaccines.
      • Dr. Marcel E. Curlin, a researcher at the University of Washington’s Institute for Health Metrics and Evaluation (IHME), has received funding from pharmaceutical companies to study COVID-19 vaccines.
      • Author Conflicts Of Interest (0%)
        None Found At Time Of Publication

      85%

      • Unique Points
        • Multidose vaccinations in both arms may increase the immune response compared to just one arm.
        • Alternating arms for multidose vaccines may produce a more powerful immune response.
        • Individuals who respond poorly to vaccines because of age or health conditions may benefit from alternating arms.
      • Accuracy
        • Alternating Arms for Vaccines May Boost Your Immunity, Study Says
        • Switching the arms increased blood antibody levels by as much as fourfold in some participants of a study conducted at Oregon Health & Science University.
      • Deception (100%)
        None Found At Time Of Publication
      • Fallacies (70%)
        The article contains an appeal to authority fallacy by stating that the results of a study conducted by Dr. Marcel E. Curlin and his team at Oregon Health & Science University should be considered when making recommendations about vaccinations.
        • ]Alternating arms may produce a more powerful immune response, a new study suggests.
      • Bias (100%)
        None Found At Time Of Publication
      • Site Conflicts Of Interest (100%)
        None Found At Time Of Publication
      • Author Conflicts Of Interest (50%)
        The author has a conflict of interest on the topic of multidose vaccinations and alternating arms. The article discusses how receiving multidose vaccinations in both arms may increase immune response.

        62%

        • Unique Points
          • If you have presented the same arm for every dose of a particular vaccine, you may want to reconsider. Alternating arms may produce a more powerful immune response.
          • , Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.
          • , even if it is not significant at this point due to most people having had multiple vaccine doses or infections, alternating arms for COVID vaccines may offer some benefit.
        • Accuracy
          • <br> Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.<br>
          • <br> even if it is not significant at this point due to most people having had multiple vaccine doses or infections, alternating arms for COVID vaccines may offer some benefit.
          • The few studies comparing the two approaches have been small and have produced mixed results. None of them has shown a big difference in immunity.<br>
          • <br> A mouse study found that a single lymph node can generate strong immunity following vaccination.
          • <br><br> In most people, extending the interval between doses by three to four months may offer a greater benefit than switching arms does.
          • Switching the arms increased blood antibody levels by as much as fourfold in some participants of a study conducted at Oregon Health & Science University.<br>
          • <br> The new study's results appear to contradict those from a German study last summer showing that rolling up the same sleeve each time might yield a better immune response.
          • Switching arms with each dose could be one part of many measures that you could easily adopt to maybe lead to a successful immune response.
        • Deception (30%)
          The article is deceptive in that it presents a study suggesting alternating arms for vaccines may produce a more powerful immune response. However, the results are mixed and not conclusive. The author also mentions other studies with contradictory findings.
          • If you’ve presented the same arm for every dose of a particular vaccine, you may want to reconsider.
        • Fallacies (75%)
          The article discusses the potential benefits of alternating arms when receiving vaccines. The study found that individuals who alternated arms showed a small increase in immunity over those who received both doses in the same arm. However, this benefit may not be significant for most people as they have already had multiple vaccine doses or infections. Additionally, there is mixed evidence on the effectiveness of alternating arms and other strategies such as extending the interval between doses may offer a greater benefit.
          • Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.
        • Bias (75%)
          The article discusses the potential benefits of alternating arms when receiving vaccines. The study found that individuals who alternated arms showed a small increase in immunity over those who received both doses in the same arm. However, this benefit may not be significant for most people as they have already had multiple vaccine doses or infections.
          • Those who alternated arms showed a small increase in immunity over those who got both doses in the same arm.
          • Site Conflicts Of Interest (50%)
            The author of the article has a conflict of interest on several topics related to COVID-19 vaccines. The author is an employee at Pfizer and has previously written about their vaccine research.
            • Author Conflicts Of Interest (50%)
              The author has a conflict of interest on the topic of COVID-19 vaccines as they have written articles in favor of vaccine mandates and are likely to be biased towards the effectiveness and safety of vaccines.