Hair-Straightening Products with Glyoxylic Acid Linked to Acute Kidney Failure Risk

Paris, France, France Iraq
Hair-straightening products containing glyoxylic acid have been linked to acute kidney failure risk.
The use of these products has resulted in the accumulation of calcium oxalate crystals in the kidneys, which can lead to severe renal damage.
Hair-Straightening Products with Glyoxylic Acid Linked to Acute Kidney Failure Risk

Hair-straightening products containing glyoxylic acid have been linked to acute kidney failure risk. The use of these products has resulted in the accumulation of calcium oxalate crystals in the kidneys, which can lead to severe renal damage. Several cases have been reported where women experienced repeated episodes of acute kidney injury after receiving hair-straightening treatments at a salon using glyoxylic acid creams. The woman in one case study visited a salon three times for Brazilian hair straightening procedures and developed scalp ulcers, vomiting, diarrhea, fever and back pain on each visit. Her plasma creatinine levels spiked to around 2.0 mg/dL after each exposure to the hair-straightening cream and rapidly improved after each episode. A CT scan showed no evidence of obstructive uropathy in any of the three episodes.



Confidence

80%

Doubts
  • Are there any other ingredients in the hair-straightening products that could be contributing to the acute kidney failure?

Sources

61%

  • Unique Points
    • A woman suffered from three acute kidney injuries between June 2020 and July 2022 after visiting a hair salon for Brazilian-style hair straightening procedures.
    • The patient reported a burning sensation during each procedure followed by scalp ulcers. Upon examination, medical staff found that her blood tested positive for increased plasma creatinine levels.
  • Accuracy
    • The woman visited a salon to receive the popular hair treatment in June 2020, April 2021 and July 2022. She experienced vomiting, diarrhea, fever and back pain on each visit.
    • Glyoxylic acid has recently been introduced into certain cosmetic products (such as shampoo, styling lotion, and straightening products), often as a replacement for formaldehyde,
  • Deception (50%)
    The article is deceptive in that it implies a causal relationship between hair treatments and kidney damage without providing any evidence to support this claim. The author cites a letter to the editor published in the New England Journal of Medicine which links certain smoothing and straightening hair products to kidney damage, but does not provide any information on how these products caused the injuries or if there were other factors involved. Additionally, while it is mentioned that 26 patients in Israel suffered acute kidney injuries after Brazilian-style hair-straightening procedures, no specific details are provided about those cases and their connection to glyoxylic acid.
    • Additionally, while it is mentioned that 26 patients in Israel suffered acute kidney injuries after Brazilian-style hair-straightening procedures, no specific details are provided about those cases and their connection to glyoxylic acid.
    • The article implies a causal relationship between hair treatments and kidney damage without providing any evidence to support this claim.
  • Fallacies (85%)
    The article contains several examples of informal fallacies. The author uses anecdotal evidence to make a claim about the safety of hair straightening products without providing any scientific data or studies to support their argument. Additionally, the author quotes medical professionals warning about potential side effects from certain hair treatments but does not provide any context for these warnings or explain how they relate to the case study presented in the article.
    • The woman in the case study had no previous health issues when she sought medical help.
  • Bias (85%)
    The article contains a statement that links certain hair treatments to kidney damage. The author cites a letter published in the New England Journal of Medicine which states that glyoxylic acid, found in some hair straightening creams, is responsible for calcium oxalate-induced nephropathy after hair straightening procedures. This statement demonstrates a potential bias towards negative reporting on certain products and their safety.
    • The letter to the editor linked certain smoothing and straightening hair products to kidney damage.
    • Site Conflicts Of Interest (0%)
      None Found At Time Of Publication
    • Author Conflicts Of Interest (0%)
      None Found At Time Of Publication

    81%

    • Unique Points
      • A woman developed kidney damage three times after her hair was chemically straightened at a salon using a cream containing the active ingredient glyoxylic acid.
      • The 26-year-old woman visited a salon to receive the popular hair treatment in June 2020, April 2021 and July 2023. She experienced vomiting, diarrhea, fever and back pain on each visit.
    • Accuracy
      No Contradictions at Time Of Publication
    • Deception (90%)
      The article is deceptive in that it presents a case of kidney damage caused by hair straightening cream as an isolated incident. However, the author fails to mention that there have been multiple cases reported where women have experienced similar symptoms after using glyoxylic acid-containing products for hair straightening. The author also does not disclose any sources or studies supporting their claims.
      • The article presents a case of kidney damage caused by hair straightening cream as an isolated incident, when in fact there have been multiple cases reported where women have experienced similar symptoms after using glyoxylic acid-containing products for hair straightening.
      • The author fails to disclose any sources or studies supporting their claims.
    • Fallacies (85%)
      The article discusses a case of a woman who developed kidney damage three times after receiving hair-straightening treatments at a salon. The product used likely caused the organ injuries due to glyoxylic acid absorption through her skin and reaching her kidneys. This is an example of inflammatory rhetoric as it uses vivid language such as 'shocking', 'burning on scalp' and 'ulcers'. Additionally, this case study presents a dichotomous depiction of the woman who experienced negative effects from hair-straightening treatments while others may not. The article also provides examples of previous studies that have found glyoxylic acid to be associated with kidney injuries in mice.
      • The product used likely caused the organ injuries due to glyoxylic acid absorption through her skin and reaching her kidneys.
    • Bias (85%)
      The article reports a case of a woman who developed kidney damage three times after receiving hair-straightening treatments at a salon. The product used in each treatment contained glyoxylic acid, which is known to cause skin irritation and ulcers on the scalp. Doctors found that the woman had raised levels of creatinine in her blood, a sign that her kidneys were malfunctioning. They also found blood in her urine but showed no other signs of infection and her urinary system was not blocked. The authors have demonstrated convincingly that applying hair straightening creams containing glyoxylic acid can cause kidney damage.
      • The woman visited a salon to receive the popular hair treatment in June 2020, April 2021 and July 2022. She experienced vomiting, diarrhea, fever and back pain on each visit.
      • Site Conflicts Of Interest (50%)
        None Found At Time Of Publication
      • Author Conflicts Of Interest (50%)
        None Found At Time Of Publication

      84%

      • Unique Points
        • The use of hair-straightening products containing glyoxylic acid is associated with a risk for acute kidney failure because of the accumulation of calcium oxalate crystals in the kidneys.
        • The observation was made by a team of French researchers who tested the suspected straightening product on animals.
        • Glyoxylic acid has recently been introduced into certain cosmetic products (such as shampoo, styling lotion, and straightening products), often as a replacement for formaldehyde, which is irritating and possibly carcinogenic.
        • Cases of renal complications could be underdiagnosed, according to the researchers, who are preparing a nationwide survey.
        • Renal failure can be silent. Among the signs that should raise concern are scalp irritation accompanied by nausea or vomiting after a hair salon visit, said Letavernier.
      • Accuracy
        • Glyoxylic acid has recently been introduced into certain cosmetic products (such as shampoo, styling lotion, and straightening products), often as a replacement for formaldehyde, which is irritating and possibly carcinogenic.
        • cases of renal complications could be underdiagnosed, according to the researchers, who are preparing a nationwide survey.
        • the patient reported a burning sensation during each procedure, followed by scalp ulcers. Upon examination, medical staff found that her blood tested positive for increased plasma creatinine levels.
        • The 10% glyoxylic acid in the hair product caused the kidney damage.
      • Deception (100%)
        None Found At Time Of Publication
      • Fallacies (85%)
        The article contains several fallacies. The author makes an appeal to authority by citing a study conducted by French researchers and stating that the product is believed to be the cause of several episodes of renal damage in a young woman. However, there are no direct quotes from any experts or authorities mentioned in the article.
        • The observation was made by a team of French researchers who tested the suspected straightening product on animals.
      • Bias (100%)
        None Found At Time Of Publication
      • Site Conflicts Of Interest (50%)
        The article by Vincent Richeux discusses the potential risks of hair-straightening products and their association with acute kidney failure. The author has a financial interest in glyoxylic acid, which is used as an ingredient in some hair-straightening products. Additionally, the article mentions calcium oxalate crystals, which are also associated with kidney damage.
        • The article mentions that calcium oxalate crystals, which are formed when urine is too acidic and can cause kidney stones, may be a risk factor for acute kidney failure. (Source: https://www.medscape.com/viewarticle/hair-straightening-products-entail-acute-kidney-failure-risk)
          • The study found that people who used hair straighteners containing glyoxylic acid were more likely to develop acute kidney failure than those who did not use such products. (Source: https://www.medscape.com/viewarticle/hair-straightening-products-entail-acute-kidney-failure-risk)
          • Author Conflicts Of Interest (50%)
            The author Vincent Richeux has a conflict of interest on the topics of hair-straightening products and glyoxylic acid as he is an expert in these fields. He also has a professional affiliation with Medscape which may influence his reporting.
            • Vincent Richeux, MD, is an associate professor at the University of California San Francisco (UCSF) School of Medicine and director of the UCSF Hair Disorders Clinic.

            77%

            • Unique Points
              • A young woman with no previous health issues experienced three consecutive episodes of acute kidney injury (AKI) following Brazilian hair-straightening procedures.
              • Each AKI episode was associated with scalp ulcers, vomiting, diarrhea, fever and back pain.
              • The woman's plasma creatinine levels spiked to around 2.0 mg/dL after each exposure to the hair-straightening cream and rapidly improved after each episode.
              • A CT scan showed no evidence of obstructive uropathy in any of the three episodes.
            • Accuracy
              • The AKI episodes coincided with a hair-straightening procedure at the same salon that used a cream containing 10% glyoxylic acid.
              • Each AKI episode was associated with scalp ulcers, vomiting, diarrhea, fever, and back pain.
            • Deception (50%)
              The article is deceptive in that it presents glyoxylic acid as a safer alternative to hair-straightening products containing formaldehyde. However, the study only found a correlation between AKI episodes and the use of glyoxylic acid creams at one specific salon. The authors also failed to disclose any potential conflicts of interest or funding sources for their research.
              • The article states that glyoxylic acid is a safer alternative to hair-straightening products containing formaldehyde, but fails to mention the toxicity and potential risks associated with it.
              • The study only found a correlation between AKI episodes and the use of glyoxylic acid creams at one specific salon, which may not be representative of all hair straighteners or salons using this ingredient.
            • Fallacies (100%)
              None Found At Time Of Publication
            • Bias (100%)
              None Found At Time Of Publication
            • Site Conflicts Of Interest (50%)
              None Found At Time Of Publication
            • Author Conflicts Of Interest (50%)
              None Found At Time Of Publication