Man Undergoes Rare Awake Kidney Transplant
A 28-year-old man from Chicago, John Nicholas, made medical history by undergoing a kidney transplant while awake at Northwestern Medicine on May 24, 2024. The procedure marked the first of its kind for the Chicago-based healthcare system.
Nicholas had been managing kidney issues since he was a teenager due to Crohn's disease. When his condition worsened in early 2024, it became clear that he would need a transplant. His childhood friend, Pat Wise, stepped up as a donor after being identified as a match.
The surgery took less than two hours and was performed using single-spinal anesthesia instead of the traditional general anesthesia. This approach allowed Nicholas to remain awake throughout the procedure and feel no pain. The benefits of this method include reduced hospital stays, decreased risks associated with general anesthesia, and increased accessibility for high-risk patients.
Nicholas was discharged from the hospital the next day, a significant improvement over the typical 2-3 day stay following a kidney transplant. He expressed excitement about being aware of every milestone reached during the procedure and feeling no pain or sensation whatsoever.
The AWAKE Program (Accelerated Surgery Without General Anesthesia in Kidney Transplantation) is now being established at Northwestern Medicine to offer similar operations for other patients who wish to undergo awake kidney transplants.
Nicholas's mother had initially planned to donate her kidney, but she was diagnosed with breast cancer and unable to proceed. Nicholas shared the news of his need for a donor with his childhood friends, one of whom stepped up as a match.
The success of this procedure marks an important milestone in the field of transplantation and opens up new possibilities for patients who may have previously been hesitant due to fears or risks associated with general anesthesia.