Serotonin Reduction Linked to Long COVID Symptoms, Suggests Penn Study

Philadelphia, Pennsylvania United States of America
A study by the University of Pennsylvania suggests that a reduction in serotonin could be the cause of Long COVID symptoms.
The SARS-CoV-2 virus can remain in the gut for an extended period, disrupting the production of serotonin.

A recent study conducted by the University of Pennsylvania has suggested a new explanation for the phenomenon known as 'Long COVID'. The study, published in October 2023, posits that a reduction in serotonin, a chemical that has various functions in the human body, could be the cause of persistent symptoms experienced by some COVID-19 survivors.

The research team at the University of Pennsylvania found that the SARS-CoV-2 virus, which causes COVID-19, can remain in the gut for an extended period, even after the virus has been cleared from the respiratory system. This lingering presence in the gut can disrupt the production of serotonin, leading to a range of symptoms including fatigue, brain fog, and depression, commonly associated with Long COVID.

The study's findings have been reported by various news outlets, including The New York Times, NBC, and the Daily Mail. While the study provides a new perspective on the cause of Long COVID, it is important to note that further research is needed to confirm these findings and to develop potential treatments based on this new understanding.


Confidence

85%

Doubts
  • The study's findings are yet to be confirmed by further research.

Sources

94%

  • Unique Points
    • The article discusses the role of serotonin in regulating mood and sleep, and how its reduction could lead to the mental health issues seen in long Covid patients.
    • It also mentions a study that found that serotonin levels were lower in the blood of long Covid patients compared to healthy individuals.
  • Accuracy
    • The New York Times article suggests that long COVID is caused by a decrease in serotonin levels. However, both the NBC Right Now and Daily Mail articles contradict this by suggesting that long COVID is caused by remnants of the virus in the gut.
  • Deception (100%)
    None Found At Time Of Publication
  • Fallacies (100%)
    None Found At Time Of Publication
  • Bias (95%)
    None Found At Time Of Publication
  • Site Conflicts Of Interest (85%)
    • The New York Times is owned by The New York Times Company, which has been criticized for its liberal bias. This could potentially influence the presentation of information in the article.
    • Author Conflicts Of Interest (100%)
      None Found At Time Of Publication

    92%

    • Unique Points
      • This article provides a video explanation of the research, offering a visual representation of how serotonin reduction could lead to long Covid symptoms.
      • It also includes an interview with one of the researchers, who explains the study in layman's terms.
    • Accuracy
      • The NBC Right Now article suggests that long COVID is caused by remnants of the virus in the gut. However, both the New York Times and Penn Medicine articles contradict this by suggesting that long COVID is caused by a decrease in serotonin levels.
    • Deception (100%)
      None Found At Time Of Publication
    • Fallacies (100%)
      None Found At Time Of Publication
    • Bias (95%)
      None Found At Time Of Publication
    • Site Conflicts Of Interest (80%)
      • NBC is owned by Comcast Corporation, which has been known to donate to both Democratic and Republican parties. This could potentially influence the presentation of information in the article.
      • Author Conflicts Of Interest (100%)
        None Found At Time Of Publication

      98%

      • Unique Points
        • The article provides a detailed explanation of the methodology used in the study, including how the researchers measured serotonin levels.
        • It also discusses the potential implications of the findings for the treatment of long Covid, suggesting that drugs that increase serotonin levels could be beneficial.
      • Accuracy
        • The Penn Medicine article suggests that long COVID is caused by a decrease in serotonin levels. However, both the NBC Right Now and Daily Mail articles contradict this by suggesting that long COVID is caused by remnants of the virus in the gut.
      • Deception (100%)
        None Found At Time Of Publication
      • Fallacies (100%)
        None Found At Time Of Publication
      • Bias (95%)
        None Found At Time Of Publication
      • Site Conflicts Of Interest (100%)
        None Found At Time Of Publication
      • Author Conflicts Of Interest (100%)
        None Found At Time Of Publication

      91%

      • Unique Points
        • This article emphasizes the potential impact of the study's findings on the understanding of long Covid, describing it as a 'chemical shift'.
        • It also includes quotes from patients who have experienced long Covid, providing a personal perspective on the condition.
      • Accuracy
        No Contradictions at Time Of Publication
      • Deception (100%)
        None Found At Time Of Publication
      • Fallacies (100%)
        None Found At Time Of Publication
      • Bias (90%)
        None Found At Time Of Publication
      • Site Conflicts Of Interest (85%)
        • The New York Post is owned by News Corp, which is known for its conservative bias. This could potentially influence the presentation of information in the article.
        • Author Conflicts Of Interest (100%)
          None Found At Time Of Publication

        89%

        • Unique Points
          • The article suggests an alternative explanation for long Covid, proposing that it could be caused by remnants of the virus in the gut.
          • It also discusses the role of the 'good hormone', suggesting that it could be involved in the development of long Covid symptoms.
        • Accuracy
          • The Daily Mail article suggests that long COVID is caused by remnants of the virus in the gut. However, both the New York Times and Penn Medicine articles contradict this by suggesting that long COVID is caused by a decrease in serotonin levels.
        • Deception (100%)
          None Found At Time Of Publication
        • Fallacies (100%)
          None Found At Time Of Publication
        • Bias (90%)
          None Found At Time Of Publication
        • Site Conflicts Of Interest (75%)
          • The Daily Mail is owned by the Daily Mail and General Trust, which has been criticized for its sensationalist and conservative bias. This could potentially influence the presentation of information in the article.
          • Author Conflicts Of Interest (100%)
            None Found At Time Of Publication