![Three Studies Show Less Intensive Cancer Treatments Can Lead to Better Outcomes and Fewer Complications](https://img.ksl.com/slc/2992/299284/29928496.jpg?filter=kslv2/responsive_story_lg)
Cancer patients often experience improved outcomes and a better quality of life with less intensive treatment, according to recent research presented at the world's largest cancer conference. In three separate studies involving ovarian, esophageal, and Hodgkin lymphoma, researchers found that scaling back treatment can be just as effective as more aggressive approaches while causing fewer complications.
Firstly, French researchers reported that avoiding lymph node removal during surgery for advanced ovarian cancer is safe and does not compromise survival. In a study of 379 patients, those who underwent less-extensive surgery had no difference in overall survival after nine years and fewer complications such as the need for blood transfusions.
Secondly, a German study compared two treatment plans for esophageal cancer: chemotherapy and surgery versus chemotherapy, surgery, and radiation. The results showed that those who received only chemotherapy and surgery had a higher survival rate (57% vs. 51%) after three years.
Lastly, researchers compared two chemotherapy regimens for advanced Hodgkin lymphoma and found that the less intensive treatment was more effective in keeping the disease in check (94% vs. 91%) for four years and caused fewer side effects.
These findings are part of a larger trend towards optimizing cancer care by questioning whether all the treatment used in the past is necessary. Thirty years ago, cancer research focused on doing more, but now researchers are asking if less can lead to better outcomes for patients. Dr. Tatjana Kolevska, medical director for the Kaiser Permanente National Cancer Excellence Program, emphasized that this question should be asked frequently.
The good news is that cancer treatment is becoming more effective and easier to tolerate with fewer short-term and long-term complications. Dr. William G. Nelson of Johns Hopkins School of Medicine also noted the importance of less intensive treatments in cancer care.
These studies were presented at an American Society of Clinical Oncology conference in Chicago.